An alternative method of SNP inclusion to develop a generalized polygenic risk score analysis across Alzheimer's disease cohorts.

Front Dement · 2023 · PMC11285631 · PMID 39081983

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highly significantno p-value reported

The lenient threshold identified a 2207-LD-clump PRS model, which, when applied to the development cohorts, yielded highly significant correlations and discriminatory accuracies of over 90% in four of the cohorts.

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