Barely Significant
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Effect of perioperative intravenous ibuprofen versus acetaminophen on postoperative opioid consumption and pain after general anesthesia: a systematic review and meta-analysis with trial sequential analysis of randomized controlled trials.

Korean J Anesthesiol · 2024 · PMC11294878 · PMID 38711266

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a decreasing trendno p-value reported
The MD in pain scores between IVB and IVA, on a scale of 10 points, showed a decreasing trend over time, with –0.83 points at 4–6 h, –0.38 points at 12 h, and no significant difference between the two groups at 24 h.

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