Fabrication of magnetic carbohydrate-modified iron oxide nanoparticles (Fe₃O₄/pectin) decorated with bimetallic Co/Cu-MOF as an effective and recoverable catalyst for the Biginelli reaction.

Introduction The Biginelli reaction represents incredibly significant multi-component reactions that generate bioactive compounds with various therapeutic and pharmacological traits, such as antitumor, antibacterial, and antioxidant. 1–3 The Biginelli reaction includes the three-component, acid-catalyzed condensation of aldehydes, β-ketoester, and urea to yield dihyd

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