Establishment and evaluation of a clinical prediction model for cognitive impairment in patients with cerebral small vessel disease.

With the increase in the total burden of CSVD, the HCY level exhibited an increasing trend, and there were significant differences between the CSVD_score1 and CSVD_score2 groups and between the CSVD_score1 and CSVD_score3 groups ( p < 0.05) (Fig. 2 b).

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