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Colchicine for the treatment of the spectrum of cardiovascular diseases: current evidence and ongoing perspectives.

J Cardiovasc Med (Hagerstown) · 2024 · PMC11296275 · PMID 38916229

Europe PMCDOI
1
hedged sentence
0.0600
closest p · 1.2× alpha
0.0600
boldest claim

The sentences

an apparent trendP = 0.060so close (0.05 < p ≤ 0.1)
Colchicine did not affect all-cause death (RR 1.08, 95% CI 0.71–1.62; P = 0.73), with a trend for a lower incidence of cardiovascular death (RR 0.82, 95% CI 0.55–1.23; P = 0.34), but an apparent trend towards a higher incidence of noncardiovascular death (RR 1.38, 95% CI 0.99–1.92; P = 0.060) 35 that gave rise to several criticisms and scepticism on the use of colchicine for secondary cardiovascular prevention in ischemic heart disease.

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