A region-confined PROTAC nanoplatform for spatiotemporally tunable protein degradation and enhanced cancer therapy.

Nat Commun · 2024 · PMC11298519 · PMID 39098906

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a decreasing trendno p-value reported

A decreasing trend also emerged for certain proto-oncogenes (e.g., Kirsten rat sarcoma viral oncogene ( Kras ), c-mesenchymal-epithelial transition factor ( Met ), Abelson murine leukemia viral oncogene homolog 1 ( Abl1 ), and murine leukemia viral oncogene homolog 1 ( Raf1 )).

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