Serum Response Factor Overexpression, a Double Trouble that May Underlie Airway Hyperresponsiveness in Asthma.

One important question that needs to be addressed is: What kind of disease state can promote SRF overexpression? Also, besides ROCK inhibition, what interventions can be made to prevent SRF overexpression? That being said, the observations made by Sun and colleagues are novel and highly significant in aiding our quest to find new drug targets for the treatment of asthma.

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