This effect diminished after 72 h and resulted in a highly significant upregulation of CNPase protein at 72 h post administration.
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Ibogaine administration following repeated morphine administration upregulates myelination markers 2', 3'-cyclic nucleotide 3'-phosphodiesterase (CNP) and myelin basic protein (MBP) mRNA and protein expression in the internal capsule of Sprague Dawley rats.
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