Determinants of Guideline-Directed Medical Therapy Implementation During Heart Failure Hospitalization.

Since prior studies had reported that GDMT utilization was related to patient age, 5 , 6 , 14 , 19 we also considered age as a continuous rather than dichotomous variable and found that increasing age had only a modest impact of borderline significance on optimal GDMT utilization.

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For patients with new diagnosis of HFrEF, the association continued to be significant after adjustment and tended toward significance after adjustment for both rehospitalization and mortality.

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Patients experiencing homelessness also had significantly lower discharge mOMT scores (0.42, 95% CI: 0.38-0.46 vs 0.48, 95% CI: 0.46-0.51; P = 0.01), with values trending toward significance in both patients with new and pre-existing diagnoses.

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