Insulin-like Growth Factor-Binding Protein 2 in Severe Aortic Valve Stenosis and Pulmonary Hypertension: A Gender-Based Perspective.

Additionally, it is interesting to note that within both the PH group and the non-PH group, there was a highly significant increase in IGF-BP2 concentration in the first 24 h post-TAVR (sPAP ≥ 40 mmHg: p = <0.001; sPAP < 40 mmHg: p = <0.001), respectively, and a significant decrease in serum concentration again in the further course from 24 h to 96 h (sPAP ≥ 40 mmHg: p = 0.032; sPAP < 40 mmHg: p = 0.021), respectively.

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