Cheminformatics-Guided Exploration of Synthetic Marine Natural Product-Inspired Brominated Indole-3-Glyoxylamides and Their Potentials for Drug Discovery.

Molecules · 2024 · PMC11314621 · PMID 39125052

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a worrying trendno p-value reported

Despite this, the testing of MIAs for antiplasmodial activities has decreased by more than 50% since 2010 [ 3 ], a worrying trend considering the recent emergence of other zoonotic diseases (i.e., SARS-CoV-2 virus) and the importance of NP scaffolds for the development of drug leads to treat these diseases.

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