Integrating transcriptomics and metabolomics to reveal the protective effect and mechanism of Bushen Kangshuai Granules on the elderly people.

In terms of sex hormones, testosterone and estradiol levels showed an increasing trend after treatment; however, this was not statistically significant ( p = 0.089 and p = 0.149, respectively).

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More specifically, after treatment, testosterone levels showed an increasing trend in the 11 male patients, estradiol levels showed a decreasing trend, and the T/E2 ratio showed an increasing trend.

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