AlphaFold2 assists in providing novel mechanistic insights into the interactions among the LUBAC subunits.

Acta Biochim Biophys Sin (Shanghai) · 2024 · PMC11322871 · PMID 38655618

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an overall trendno p-value reported

The RMSD results indicated that the protein structures of HOIP (466‒695) and HOIL-1L-UBL remained relatively stable throughout the simulation, with an overall trend of initial increase followed by subsequent decrease, and the overall RMSD values were below 1 nm.

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