Late sporogonic stages of <i>Plasmodium</i> parasites are susceptible to the melanization response in <i>Anopheles gambiae</i> mosquitoes.

Indeed, the mean number of melanized oocysts in these mosquitoes was similar to control, and melanization prevalence was marginally significant ( Figure 1E ) and much lower than that scored for day-14 oocysts (compare ds CLIPA2 / A14 pie charts in Figure 1E with those in Figures 1A, B ), suggesting that oocysts’ susceptibility to the melanization response is dramatically enhanced after their walls start to rupture.

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