Submacular Hemorrhage during Neovascular Age-Related Macular Degeneration: A Meta-Analysis and Meta-Regression on the Use of tPA and Anti-VEGFs.

After imputing missing studies in the funnel plot, adjustment of effect size for possible publication bias using the trim-and-fill correction results in decreased, albeit still highly significant estimate of pooled mean difference (adjusted = −0.36 logMAR; 95% CI: −0.44; −0.28; p < 0.0001).

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