Further consideration showed that Δaap1 , Δaap2 , Δaap1Δaap2 , Δaap4 , Δaap5 , Δaap6 , Δaap8 , Δaap9 , Δaap10 , and Δaap9Δaap10 generally showed phenotypic attributes not far from the wt with respect to oxidative and osmotic resistance, haploid fruiting, cell wall and membrane destabilizers, secretion of phospholipase, urease, melanin, and to some extent capsule formation; however, the stress implication of Δaap4Δaap5 is always highly significant compare to the wt [ 9 , 13 ].
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A Limited Number of Amino Acid Permeases Are Crucial for <i>Cryptococcus neoformans</i> Survival and Virulence.
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