Evaluations of Biomarkers CDX1 and CDX2 in Gastric Cancer Prognosis: A Meta-analysis.

Correlation of CDX2 with clinicopathological parameters CDX2 expression was inversely associated with lymph node metastasis (high CDX2 expression was associated with decreased lymph node metastasis (RR=1.52, 95% CI: 1.29-1.79, P<0.00001) ( Figure 5 ) however, CDX2 expression was significantly higher in poorly differentiated gastric cancers (RR=1.52, 1.52; and significantly higher in well-differentiated and latent gastric cancers marginal significance compared with 95% CI: 1.22-1.87, P<0.00001) ( Figure 6 ) was observed (RR =0.82, 95%).CI =0.67-1.01, P=0.07) ( Figure 8 ).

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