Although statistical analysis did not reveal significant differences in symptom scores between Grade 1 and Grade 2 or between Grade 1 and Grade 3, there was an evident trend toward higher symptom scores in Grade 4 compared to Grade 1, with statistical significance observed for chest tightness.
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Association of low attenuation area scores with pulmonary function and clinical prognosis in patients with chronic obstructive pulmonary disease.
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The sentences
As the COPD grade increased, there was an overall trend toward higher symptom scores across all categories.