The generated heatmap showed that Akkermansia, g_AF12 (Rikenellaceae family), g_Cc_115 (Erysipelotrichaceae family), Rikenella, Allobaculum, Adlercreutzia, Lactococcus and other OTUs had a highly significant positive association with a wide spectrum of metabolites including 3-hyroxysobutyrate dehydrogenase, UDP-4-keto hexauronic acid decarboxylation, L-threonine 3-dehydrogenase, UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase, uronate dehydrogenase, and alcohol dehydrogenase.
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Soybean oil-based HFD induces gut dysbiosis that leads to steatosis, hepatic inflammation and insulin resistance in mice.
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