Further, is the marginal significance driven by the rare allele (AA, n=9)?
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CHRM3 (rs2165870) gene polymorphism is related to postoperative vomiting in female patients undergoing laparoscopic surgery. Prospective observational study.
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P-values need to be adjusted for the 9 tests conducted (Table 3), and a marginally significant p-value of 0.022 will no longer be significant after adjustment.