The potential therapeutic role of itaconate and mesaconate on the detrimental effects of LPS-induced neuroinflammation in the brain.

J Neuroinflammation · 2024 · PMC11337794 · PMID 39164713

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

a slight trendno p-value reported

Only in the CA1 subregion of WT mice a slight trend towards increased CD68 levels after LPS-injection was observed (Suppl. 3B, WT-Saline vs.

also in 4,078 other papers

highly significantno p-value reported

The LPS-induced expression of IL-1β and IL-6 was reduced by both metabolites in a highly significant manner (Fig. 6 , untreated vs.

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.