However, due to the limited number of study controls (n = 2), although Met demonstrated an increasing trend for Beclin-1/GAPDH, P62/GAPDH, and LC3-II/LC3-I, no statistically significant differences were observed compared to these values associated with Dox treatment.
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Reliability of Metformin's protective effects against doxorubicin-induced cardiotoxicity: a meta-analysis of animal studies.
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