In the 1G11 group, the rate of CD8 + /CD45 + in tumor tissues showed an increasing trend compared with the mIgG control, (Fig. 4 D), and the rates of CD3 + /CD45 + and CD4 + /CD45 + increased significantly (Fig. 4 D).
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Antagonist anti-LIF antibody derived from naive human scFv phage library inhibited tumor growth in mice.
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