Miniaturized Fab' imaging probe derived from a clinical antibody: Characterization and imaging in CRISPRi-attenuated mammary tumor models.

The measurements of background- and noise-adjusted imaging signal averaged using 50–80 individual cells showed that the differences between the WT and CRISPRi cell groups were highly significant ( p < 0.01) with approximately 2-times higher binding/uptake by WT cells observed at the early time point (30 min).

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