Spatial extent as a sensitive amyloid-PET metric in preclinical Alzheimer's disease.

In the combined EXT and LVL models (Model 2), only EXT remained a significant predictor of increasing FTP SUVR over time in MTL and TEMP (Table 2 ), though increasing baseline LVL was significantly associated with decreasing TEMP tau proliferation and a marginally significant decrease in MTL tau over time.

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