The Absence of Items Addressing Increased Appetite or Weight in Depressive-Symptom Questionnaires: Implications for Understanding the Link between Major Depressive Disorder, Antidepressants, and Obesity.

A retrospective analysis from an ongoing multi-center clinical study conducted by the European Group for the Study of Resistant Depression (GSRD) found that an elevated BMI was associated with higher suicidality, longer psychiatric hospitalizations, and earlier age of MDD onset, also reporting a statistical trend of higher BMI with treatment resistance [ 56 ].

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