Inhibition of Calcineurin with FK506 Reduces Tau Levels and Attenuates Synaptic Impairment Driven by Tau Oligomers in the Hippocampus of Male Mouse Models.

Additionally, we observed a decreasing trend of Tau and pTau after FK506 treatment in the CA1 region ( Figure 3 e–h).

also in 47,180 other papers

Western blot analyses of autophagic markers indicated an overall trend toward restoration ( Supplementary Figure S6 ), aligning closely with the previous observations in humans [ 29 ].

also in 4,871 other papers