An intronic copy number variation in Syntaxin 17 determines speed of greying and melanoma incidence in Grey horses.

The perfect association between copy number of the duplicated sequence and the fast/slow greying phenotype including both Connemara ponies from Sweden and Thoroughbreds from Japan is highly significant (Fisher’s exact test; P = 4.9 × 10 -6 ) (Fig. 3c , Supplementary Fig. 4a , Supplementary Table 2 ).

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