3 , 21 A pooled analysis of the Southwest Oncology Group (SWOG) clinical trials observed an increasing trend from 23% to 42% in obesity among patients participating in clinical trials between 1985 and 2020, mirroring US adult obesity rates. 22 In the GIM2 trial, nearly half of the population was overweight or obese at diagnosis, underlining the critical relevance of this condition among women with breast cancer diagnosis also in Italy.
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Efficacy of adjuvant chemotherapy schedules for breast cancer according to body mass index: results from the phase III GIM2 trial.
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