The MR results show that phylum Proteobacteria and genus Ruminococcaceae UCG013 exhibited a notable adverse causal effect on HIV infection (with an OR exceeding 2), whereas genus Clostridium sensu stricto 1 and family Erysipelotrichaceae acted as fairly significant protective factors for HIV (with an OR below 0.5).
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Causal relationships between gut microbiota, plasma metabolites, and HIV infection: insights from Mendelian randomization and mediation analysis.
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