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Mechanism of YJKL Decoction in Treating of PCOS Infertility by Integrative Approach of Network Pharmacology and Experimental Verification.

Drug Des Devel Ther · 2024 · PMC11366254 · PMID 39219692

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highly significantno p-value reported
42 Kaempferol, as a natural and highly significant active flavonoid molecule, inhibits tumors by activating the AMPK/Nrf2/HO-1 signaling pathway, thereby reducing apoptosis, decreasing inflammatory responses, and improving oxidative stress. 43 KEGG enrichment analysis results reveal that YJKL Decoction involves multiple signaling pathways in the treatment of PCOS, primarily the TNF signaling pathway and the HIF-1 signaling pathway.

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