There was a decreasing trend of Bcl-2 protein expression, while there was an increasing trend of Bax, cleaved caspase-3 and cleaved caspase-9 protein expressions in the UD group, and these trends showed more pronounced in the GFD group (Fig. 2 B).
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Glucose fluctuations aggravate cardiomyocyte apoptosis by enhancing the interaction between Txnip and Akt.
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