Notably, three MS2-annotated metabolites were highly significant (FDR < 0.05) including Perio-increased L-urobilin (HMDB0004159, log 2 FC: 0.94) and kynurenic acid (KYNA, HMDB0000715, log 2 FC: 0.64) as well as Perio-decreased norbuprenorphine glucuronide (NBUP-G).
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Integrative microbiome and metabolome profiles reveal the impacts of periodontitis via oral-gut axis in first-trimester pregnant women.
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