Differential expression analysis of proteomic data (volcano plot, Figure 2 B-C) resulted in highly significant expression signatures (false discovery rate <0.05) with 227 proteins differentially regulated in ET (113 increased and 114 decreased) and 166 in PV (122 increased and 44 decreased) compared with healthy donors (see supplemental Tables 5 and 6 for full list).
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Platelet proteomic profiling reveals potential mediators of immunothrombosis and proteostasis in myeloproliferative neoplasms.
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