highly significantP -value <0.0005
In an analysis of variance (ANOVA) of absolute abundance of Faecalibacterium quantified by qPCR, with factors subject, presence/absence of tannins, allele at MEL6A, and all interactions between them, all factors were highly significant ( P -value <0.0005) except the interaction term for tannin and MEL6A allele ( Supplementary Table 8 ).