Single-cell and spatial transcriptome analyses reveal tertiary lymphoid structures linked to tumour progression and immunotherapy response in nasopharyngeal carcinoma.

Along with the developmental path from CD8_C8_CXCL13 to CD8_C11_HAVCR2 cells, we observed an increasing trend for exhaustion scores but a decreasing trend for stem-like scores (Fig. 7d , Supplementary Fig. 13c , and Supplementary Data 4 ).

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