Dual Role of Necroptosis in Cervical Cancer: Promoting Tumor Aggression and Modulating the Immune Microenvironment via the JAK2-STAT3 Pathway.

The expression levels of RIPK1, RIPK3, MLKL and the protein levels of p-RIPK3 and p-MLKL exhibited an elevated trend when bevacizumab was added in CC cells ( Figure 3 B-E ), indicating that bevacizumab induces the necroptosis of CC cells.

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Besides, the protein level of CD3D, JAK2, STAT3 and p-STAT3 detected by WB exhibit an increasing trend in the necroptosis group ( Figure S6 H ).

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