Analgesic effect of ultrasound-guided extraoral mandibular nerve block compared to intraoral conductive block of the inferior alveolar nerve after lower third molar alveolectomy: a clinical prospective study.

However, since our results are strongly convincing and since the statistical difference of the primary outcome (time to pain onset) was highly significant ( P < 0.001), which proved sufficient power of the study, we believed that similar results would be achieved with the study that includes random allocation of patients to study and control group, and with the use of placebo in the control group.

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