Paeoniflorin protects hepatocytes from APAP-induced damage through launching autophagy via the MAPK/mTOR signaling pathway.

Both solvent-accessible surface area (SASA) and radius of gyration (Rg) were reflected the tightness of the complex protein structure during simulation, and our results indicated a decreasing trend in both variables, suggesting an increase in protein tightness structure and a good combination of p38-PF complex (Fig. 7 C, D).

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