The oncogenic fusion protein EML4-NTRK3 requires three salt bridges for stability and biological activity.

Heliyon · 2024 · PMC11381775 · PMID 39253179

Europe PMC DOI

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closest p

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The sentences

highly significantno p-value reported

However, for each of the double mutants as well as for the triple salt bridge mutant, the effects on P-MAPK, P-STAT3, and P-PLCγ1 are highly significant.

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