In our study, despite the results of sensitivity analysis showing heterogeneity and pleiotropy, the causal effects of urate on TL shortening were highly significant (OR: 0.80, 95%CI: 0.68–0.94, P IVW = 0.006).
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Genetic liability to human serum metabolites is causally linked to telomere length: insights from genome-wide Mendelian randomization and metabolic pathways analysis.
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