Reconstitution of CD4 + T cells was also observed in lung tissue at endpoint in the 2 cART groups, with each exhibiting a highly significant increase (mean, 3.99% and 5.72% for D1MT+cART and cART groups, respectively), relative to untreated RMs (mean, 1.30%) ( Figure 6D ).
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Indoleamine-2,3-dioxygenase inhibition improves immunity and is safe for concurrent use with cART during Mtb/SIV coinfection.
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