The use of controlled human infection models to identify correlates of protection for invasive <i>Salmonella</i> vaccines.

Front Immunol · 2024 · PMC11385307 · PMID 39257585

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borderline significantno p-value reported

Ty21a generated a borderline significant increase in anti-LPS IgG only, but when looking at antibody secreting cell titres (as measured by ELISPOT) both vaccines induced a significant increase in anti-LPS ASC and anti-H ASC compared with placebo.

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