Impact of primary tumor sidedness and sex on prognosis and anti-epidermal growth factor receptor antibody efficacy in BRAF-mutant metastatic colorectal cancer: a pooled analysis of AIO studies FIRE-1, CIOX, FIRE-3, XELAVIRI, and VOLFI.

An interaction test revealed significant results for OS and showed a trend toward significance for PFS between primary tumor sidedness and the treatment arms in the respective study (OS: P = 0.01; PFS: P < 0.01); additionally, a significant interaction was observed between anti-EGFR and non-anti-EGFR treatment and PTS for both OS ( P < 0.010) and PFS ( P = 0.05).

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An interaction test revealed significant results for OS and showed a trend toward significance for PFS between primary tumor sidedness and the treatment arms in the respective study (OS: P = 0.01; PFS: P < 0.01); additionally, a significant interaction was observed between anti-EGFR and non-anti-EGFR treatment and PTS for both OS ( P < 0.010) and PFS ( P = 0.05).

also in 10,348 other papers