CYP3A4 mRNA expression levels showed a decreasing trend.
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Cadmium causes spleen toxicity in chickens by regulating mitochondrial unfolded protein response and nuclear receptors response.
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Effects of Cd on Mitochondrial Functional Protein Genes in Chicken Spleen The mRNA expression levels of VDAC-1 and Cyt-C ( Figures 6A and B ) showed an increasing trend with the gradual increase of Cd exposure dose, while the levels of COA6 ( Figure 6C ) showed a decreasing trend.