RING1 missense variants reveal sensitivity of DNA damage repair to H2A monoubiquitination dosage during neurogenesis.

Nat Commun · 2024 · PMC11387726 · PMID 39256363

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highly significantno p-value reported

The mechanistic relationship between relative H2AK119ub1 dosage across chromosomes, genes and functional elements and the specificity of these H2AK119ub1 functions is a highly significant unanswered question.

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