However, when adding gender and education as additional covariates, the indirect effect was again seen to be weakened, with the CIs marginally overlapping with zero (est = 0.069, 95% CI [-0.010, 0.176]) and the direct effect almost reached statistical significance ( c ’ = 0.069, p = .057) (see supplementary Results 2).
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Effects of glycaemic control on memory performance, hippocampal volumes and depressive symptomology.
2
0.0570
0.0570
The sentences
Adding gender and education weakened the mediation effects to borderline significance, while adding ICV abolished it.