Indeed, we found strong and highly significant positive correlations between T1 cytokine responses and expression of a broad array of adaptive and innate effector pathways, whereas exhaustion pathways (CTLA-4 and PD-1) were suppressed in triple top responders ( Supplementary Figure S7 ).
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Antigen-specific T helper cells and cytokine profiles predict intensity and longevity of cellular and humoral responses to SARS-CoV-2 booster vaccination.
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