<i>Lespedeza homoloba</i> enhances the immunosuppressive milieu of adipose tissue and suppresses fasting blood glucose.

By contrast with the subcutaneous adipose tissue, LH treatment in the spleen resulted in a substantial decrease in Tregs with a minimal effect on CTLA-4 + Tregs, a notable increase in Th17 cells and the Th17/Treg ratio and an increasing trend in CD8 + T cells.

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In subcutaneous adipose tissue, IL-10 + Tregs showed a decreasing trend in 0.1% LH-treated mice and an increasing trend in 0.2% LH-treated mice, similar to the trend observed for blood adiponectin levels.

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