PPAR-α Insufficiency Enhances Doxorubicin-Induced Nephropathy in PPAR-α Knockout Mice and a Murine Podocyte Cell Line.

Additionally, a significant increase in the serum levels of NEFA, a significant decrease in TC levels, and a decreasing trend in the glucose levels in PAKO mice were noted after 48-h fasting compared to those in the WT mice ( Figure 1 B–D).

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